The Vakoc Laboratory

Transcriptional Dependencies in Cancer

Our laboratory studies how transcription factors, chromatin proteins, and signaling molecules cooperate to maintain the cancer cell state. We make extensive use of CRISPR-Cas9 genetic screens, epigenomics, and biochemistry to study gene regulatory mechanisms. Our goal is to develop a new generation of therapies that reprogram transcription to eliminate cancer cells.

Ph.D. student and Post-doc positions are available