Discovery of Epigenetic Vulnerabilities in Cancer
Our laboratory studies how transcription factors, chromatin proteins, and signaling molecules cooperate to maintain the cancer cell state. We make extensive use of CRISPR-Cas9 genetic screens, epigenomics, and biochemical approaches in our studies of gene regulatory mechanisms. Our goal is to develop a new generation of therapies that reprogram transcription to eliminate cancer cells.
Post-doc positions are available