The Vakoc Laboratory

Discovery of Epigenetic Vulnerabilities in Cancer

Our laboratory studies how transcription factors, chromatin proteins, and signaling molecules cooperate to maintain the cancer cell state. We make extensive use of CRISPR-Cas9 genetic screens, epigenomics, and biochemical approaches in our studies of gene regulatory mechanisms. Our goal is to develop a new generation of therapies that reprogram transcription to eliminate cancer cells.

Post-doc positions are available