The Vakoc Laboratory

Cancer Drug Target Discovery and Mechanisms

Our lab seeks to discover drug targets by applying genetic screens to human cancer cells. This genetic screening campaign has overwhelmingly led us to DNA-binding transcription factors as an opportunity for developing new medicines in oncology. To develop pharmacology against these challenging targets, we apply the latest innovations in high-throughput genetics, biochemistry, genomics, and structural biology to gain deep insights into cancer-promoting transcriptional mechanisms.

Ph.D. student and Post-doc positions are available